E-cadherin is required for gastrulation cell movements in zebrafish
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چکیده
منابع مشابه
E-cadherin is required for gastrulation cell movements in zebrafish
E-cadherin is a member of the classical cadherin family and is known to be involved in cell-cell adhesion and the adhesion-dependent morphogenesis of various tissues. We isolated a zebrafish mutant (cdh1(rk3)) that has a mutation in the e-cadherin/cdh1 gene. The mutation rk3 is a hypomorphic allele, and the homozygous mutant embryos displayed variable phenotypes in gastrulation and tissue morph...
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Beginning during the late blastula stage in zebrafish, cells located beneath a surface epithelial layer of the blastoderm undergo rearrangements that accompany major changes in shape of the embryo. We describe three distinctive kinds of cell rearrangements. (1) Radial cell intercalations during epiboly mix cells located deeply in the blastoderm among more superficial ones. These rearrangements ...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2005
ISSN: 0925-4773
DOI: 10.1016/j.mod.2005.03.008